{"slip": { "id": 133, "advice": "If you find yourself distressed about something, ask yourself if it will still matter tomorrow or next week or next month."}}
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{"type":"standard","title":"Mitotic catastrophe","displaytitle":"Mitotic catastrophe","namespace":{"id":0,"text":""},"wikibase_item":"Q6881914","titles":{"canonical":"Mitotic_catastrophe","normalized":"Mitotic catastrophe","display":"Mitotic catastrophe"},"pageid":22754707,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/0/06/RPE_cell_that_has_been_treated_with_taxol_and_undergone_mitotic_catastrophe.png","width":256,"height":304},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/0/06/RPE_cell_that_has_been_treated_with_taxol_and_undergone_mitotic_catastrophe.png","width":256,"height":304},"lang":"en","dir":"ltr","revision":"1261370985","tid":"0c268337-b33d-11ef-9480-65c19bc07c7a","timestamp":"2024-12-05T19:13:45Z","description":"Mechanism of cell death","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Mitotic_catastrophe","revisions":"https://en.wikipedia.org/wiki/Mitotic_catastrophe?action=history","edit":"https://en.wikipedia.org/wiki/Mitotic_catastrophe?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Mitotic_catastrophe"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Mitotic_catastrophe","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Mitotic_catastrophe","edit":"https://en.m.wikipedia.org/wiki/Mitotic_catastrophe?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Mitotic_catastrophe"}},"extract":"Mitotic catastrophe has been defined as either a cellular mechanism to prevent potentially cancerous cells from proliferating or as a mode of cellular death that occurs following improper cell cycle progression or entrance. Mitotic catastrophe can be induced by prolonged activation of the spindle assembly checkpoint, errors in mitosis, or DNA damage and operates to prevent genomic instability. It is a mechanism that is being researched as a potential therapeutic target in cancers, and numerous approved therapeutics induce mitotic catastrophe.","extract_html":"
Mitotic catastrophe has been defined as either a cellular mechanism to prevent potentially cancerous cells from proliferating or as a mode of cellular death that occurs following improper cell cycle progression or entrance. Mitotic catastrophe can be induced by prolonged activation of the spindle assembly checkpoint, errors in mitosis, or DNA damage and operates to prevent genomic instability. It is a mechanism that is being researched as a potential therapeutic target in cancers, and numerous approved therapeutics induce mitotic catastrophe.
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{"slip": { "id": 108, "advice": "Don't ever name files or folders using the word \"Final\"."}}
{"fact":"Spanish-Jewish folklore recounts that Adam\u2019s first wife, Lilith, became a black vampire cat, sucking the blood from sleeping babies. This may be the root of the superstition that a cat will smother a sleeping baby or suck out the child\u2019s breath.","length":245}